The Arnas Blog
The Arnas Blog
Insights on fluorescence microscopy, lightsheet imaging, big data, and AI-enabled scientific workflows
10 posts
Deconvolution Microscopy: Fundamentals, Applications, and Reproducible Results
A technical guide to deconvolution microscopy — what the point spread function is, how iterative algorithms recover lost signal, which modalities benefit most, and what it takes to get reproducible results across labs.
Arnas Verify: Offline License Enforcement Without the Phone-Home
A small, public reference implementation showing how to bind a signed license file to one machine — locally, transparently, and without any network calls.
The True Cost of Research Software
The license fee is rarely the number that decides anything. A look at what the standard cost frameworks miss — and a tool built to price the adoption, not just the software.
Introducing Bead Analyzer for 3D PSF Characterization
Bead Analyzer is a new open-source tool that makes 3D PSF characterization fast, accurate, and reproducible — with a GUI, a command line, and bead detection that uses AI.
Sub-Micron 3D Imaging with ClearScope
ClearScope is a new Light-Sheet Theta Microscope that achieves sub-micron resolution on specimens of unlimited lateral size — including intact primate brains and human tissue.
Zarr for Windows: So Many Files, So Little Time
OME-Zarr is the future of microscopy data — but Windows hates millions of small files. Here is why it happens and three practical fixes that do not require abandoning Zarr.
SLICE: Affordable Lightsheet Microscopy
SLICE is a new turnkey lightsheet microscope that delivers high-performance 3D imaging at a fraction of the cost of traditional LSFM systems — starting under $100K.
Did COVID Break the Wheel of Fortune?
We audited 6 seasons of Wheel of Fortune data across 6,371 contestants to test whether the COVID-era plastic cap changed the game — and found something unexpected.
Compressing 3D Microscopy Images Without Losing Science
Light sheet microscopy generates terabytes of data per scan. Learn how to choose the right compression level without sacrificing scientific integrity.